窦性心率震荡与冠状动脉病变的相关性及PTCA对其影响

目的 探讨窦性心率震荡(HRT)各指标与冠状动脉病变的相关性及经皮冠状动脉腔内成形术(PTCA)对其影响.方法 选择150例患者进行冠状动脉造影(CAG)和24 h动态心电图(AECG)监测,对CAG阳性组于PTCA术后第1天和第7天进行AECG监测并随访观察心功能与HRT的关系,分别计算各阶段HRT的震荡初始(TO)、震荡斜率(TS)和震荡斜率起始时间(TT)值. 结果 CAG阳性组TO和TT值显著高于阴性组(P<0.05或0.001),TS显著低于阴性组(P<0.001);冠状动脉多支病变组TO和TT显著高于单支病变组(P<0.05或<0.001),而TS显著低于单支病变组(P<0.001);PTCA术后第1天单支或多支病变组TO、TS和TT均较术前明显改善(P<0.001),术后随访左心功能不全组HRT现象均较无左心功能不全组明显减弱(P<0.05或<0.001). 结论 HRT与冠状动脉病变程度相关,PTCA术后HRT明显改善,后期的心功能不良是影响HRT现象减弱的重要因素之一.

Correlation of heart rate turbulence to coronary lesions and its changes following percutaneous transluminal coronary angioplasty

Objective To investigate the correlation between heart rate turbulence(HRT) and coronary lesion and the effects of percutaneous transluminal coronary angioplasty(PTCA) on HRT.Methods This study involved 150 patients undergoing 24-hour ambulatory electrocardiograply(AECG) and elective coronary angiography(CAG).AECG was monitored on the first day and 7 days after PTCA in 108 patients with positive CAG findings,and the variation of HRT and cardiac functions were observed.The turbulence onset(TO),turbulence slo...