1. Divisions of Cytogenetics and Hematology/Oncology, Departments of Medicine and Laboratories, The Jewish Hospital and Medical Center of Brooklyn, Brooklyn, New York, USA;2. SUNY Downstate Medical Center, Brooklyn, New York, USA.
Abstract:
Chromosome analysis can be performed by culturing cerebrospinal fluid from patients with CNS leukemia. The quality of the metaphase spreads are adequate for banding studies. This approach is useful, especially when the bone marrow is difficult to aspirate or when CNS involvement is the only manifestation of the leukemia.