| 不同基质淫羊藿苷软膏剂的制备及药物释放测定 |
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| 引用本文： | 娄志华,刘艳丽. 不同基质淫羊藿苷软膏剂的制备及药物释放测定[J]. 中成药, 2001, 23(5): 321-323 |
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| 作者姓名： | 娄志华 刘艳丽 |
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| 作者单位： | 1. 辽宁中医学院附属医院,辽宁,沈阳,110032
2. 沈阳药科大学,辽宁,沈阳,110015 |
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| 摘 要： | 目的：采用乳剂型软膏基质、水溶性软膏基质、油溶性软膏基质分别制备成淫羊藿苷软膏剂A、B、C对其药物释放进行测定。方法：采用紫外分光光度法在波长270nm处测定最大吸收值，计算含量。比较了各基质对淫羊藿苷释放速度的影响。结果：3种样品的释药速度快慢依次为：A＞B＞C。结论：乳剂型软膏基质制成的淫羊藿苷制剂释药速度最快。
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| 关 键 词： | 淫羊藿苷 药物释放速度 软膏剂 基质 |
| 文章编号： | 1001-1528(2001)05-0321-02 |
| 修稿时间： | 2001-01-15 |
Preparation of Different Bases of Icariin Ointment and Determination of Drug Releasing Rate |
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| LOU Zhi-hua,LIU Yan-li. Preparation of Different Bases of Icariin Ointment and Determination of Drug Releasing Rate[J]. Chinese Traditional Patent Medicine, 2001, 23(5): 321-323 |
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| Authors: | LOU Zhi-hua LIU Yan-li |
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| Abstract: | Objective:To determine the drug releasing rate of Icariin Ointment made of emulsion ointment base (A), water-soluble base (B) and oilsoluble bases (C), respectively. Methods: The maximum absorption value was determined by UV at 270 nm, and the drug content was calculated. Also the effects of different ointment bases on the icariin releasing rate were determined.Results: The order of drug releasing rates of three samples from fast to slow were: A>B>C.Conclusion: The drug releasing rate of Icariin Ointment made of emulsion ointment base is the fastest. |
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| Keywords: | Icariin Ointment drug releasing rate icariin |
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