Bone Loss and Recovery in Regional Migratory Osteoporosis |
| |
Authors: | C Trevisan S Ortolani |
| |
Institution: | (1) Clinica Ortopedica, Università degli Studi di Milano Bicocca – Osp. S.Gerardo, Monza;, IT;(2) Istituto Auxologico Italiano, IRCCS, Milan, Italy, IT |
| |
Abstract: | Regional migratory osteoporosis (RMO) is a migrating arthralgia of the weight-bearing joints of the lower limb associated
with focal osteoporosis. Little information is available on a quantitative assessment of systemic or local osteoporosis. In
this study, we report three cases of RMO in which spine, hip and whole body serial assessments of bone mass have been evaluated
to outline their extent and time course of changes. Systemic osteoporosis, with a prevalent involvement of the mainly trabecular
skeletal sites, was present in all the patients, with T-scores below −2.5 at both the lumbar spine and femoral neck. Bone loss in acute episodes ranged from −75.5% to −14.7% and
appeared related to the severity of the episode. In acute episodes the demineralizing process affected the whole limb from
the hemipelvis to the foot: the bone loss ranged from −33.6% to −3.5% at sites with prevalent trabecular composition and from
−19.1% to −1.1% at sites with prevalent cortical composition. Bone recovery was complete in one episode out of six. In the
other five cases, the average residual bone loss was 26% (range 13.9–32.7%). Our observations suggest that RMO occurs in subjects
with systemic osteoporosis and densitometric assessment may aid in the clinical management.
Received: 12 February 2002 / Accepted: 17 June 2002
Correspondence and offprint requests to: Carlo Trevisan, MD, Clinica Ortopedica, Università degli Studi di Milano Bicocca, Azienda Osp.S.Gerardo, Via Donizetti, 106-20052
Monza (MI), Italy. Tel: +39 039 2332322. Fax +39 039 2302905. e-mail: trevisan@progetto3000.it |
| |
Keywords: | :Bone loss – Bone mineral density – Dual-energy X-ray absorptiometry – Regional migratory osteoporosis – Transient osteoporosis of the hip |
本文献已被 SpringerLink 等数据库收录! |
|