以尿道炎表现的男性性病患者支原体感染研究

目的:了解支原体在男性性病患者中的感染现状及耐药情况.方法:应用淋球菌血琼脂培养基以及支原体鉴定定量和药敏试条对5 354例拟诊性病患者取材做淋球菌培养以及支原体培养和药敏试验.结果:在拟诊性病患者中,病原体阳性率达24.9%(1 333/5 354),其中:淋球菌占总阳性率5.0%(67/1 333),沙眼衣原体(Ct)占31.4%(418/1 333),解脲脲原体(Uu)占57.2%(763/1 333),人型支原体(Mh)占6.4%(85/1 333),Uu＋Mh阳性率9.1%(121/1 333);对药物的耐药率依次为:氧氟沙星(54.7%)、红霉素(44.9%)、四环素(19.9%)、强力霉素(19.6%)、交沙霉素(15.6%)和原始霉素(11.6%).结论:在以尿道炎表现的男性性病中以Uu感染为主,患者年龄以21～40岁为主;支原体感染的耐药情况严重,在临床工作中同时进行支原体培养和药敏试验对临床用药具有重要意义.

Study of Mycoplasma Infection and Drug Susceptibility Testing in Male Venereal Patients with Manifestation of Urethritis

Objective:To observe the infection and drug resistance of mycoplasma in male venereal patients. Methods:To the samples of 5 354 patients who were suspected of venereal diseases, Neisseria gonorrhoeae culture, mycoplasma culture and drug susceptisility testing were done. Results:In these patients, the positive rate of pathogen was 24.9%(1 333/5 354). Among them, the proportion of neisseria gonorrhoeae, chlamydi trachomatis (Ct), ureaplasma urtalyticum (Uu), mycoplasma hominis (Mh) and Uu confirmed with Mh was 5.0%(67/1 333), 31.4% (418/1 333), 57.2%(763/1 333), 6.4%(85/1 333) and 9.1%(121/ 1 333) respectively. The result of drug susceptibility testing indicated that 54.7% was Ofloxacine resistance, 44.9% was erythromycine, 19.9% was tetracycline, 19.6% was doxycycline, 15.6% was josamycine and 11.6% was pristinamycine one. Conclusion:In male venereal patients manifestation of urethritis, Uu was the major pathogen. Most of venereal patients was between 21 and 40. Drug resistance of mycoplasma was severe. Culture and drug susceptibility testing of mycoplasma were important for clinical therapy.