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Orthostatic hypotension does not predict recurrent falling in a nursing home population
Affiliation:1. Diabetes Centre, Isala, P.O. Box 10400, 8000 G.K. Zwolle, The Netherlands;2. TriviumMeulenbeltZorg, PC Borstlaan 10, 7555 SH Hengelo, The Netherlands;3. University Medical Centre Groningen and University of Groningen, Department of General Practice, Antonius Deusinglaan 1, Groningen 9713 AV, The Netherlands;4. University Medical Centre Groningen and University of Groningen, Department of Internal Medicine, Hanzeplein 1, 9700 RB Groningen, The Netherlands;5. Langerhans Medical Research Group, P.O. Box 10400, 8000 G.K. Zwolle, The Netherlands;6. Isala, Department of Internal Medicine, Dokter van Heesweg 2, 8025 AB Zwolle, The Netherlands;1. International Health Services, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea;2. Department of Family Medicine, Seoul National University Hospital, Seoul, Republic of Korea;3. Department of Family Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea;4. Cancer Policy Branch, National Cancer Control Research Institute, National Cancer Center, Goyang, Republic of Korea;5. Department of Family Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea;6. JW Lee Center for Global Medicine, College of Medicine, Seoul National University, Seoul, Republic of Korea;1. Department of Geriatry, Hôpitaux Universitaires Saint Louis—Lariboisière Assistance Publique des Hôpitaux de Paris, Paris, France;2. University Paris Diderot, PRES Sorbonne Paris Cité, France;3. UMR-S 942, INSERM, Paris, France;4. Department of Anesthesiology and Critical Care Medicine, Hôpitaux Universitaires Saint Louis—Lariboisière, Assistance Publique des Hôpitaux de Paris, Paris, France;5. Department of Cardiology, Hôpitaux Universitaires Saint Louis − Lariboisière, Assistance Publique des Hôpitaux de Paris, Paris, France;6. Division of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland;7. Division of Cardiology and Cardiovascular Medicine, Fondazione Toscana Gabriele Monasterio, Pisa, Italy;8. Scuola Superiore Sant''Anna, Pisa, Italy;1. United Nations Population Division, Two UN Plaza, DC2-1910, New York, NY 10017, USA;2. Department of Community and Family Medicine & Department of Sociology, Duke University, Durham, NC, USA;3. Independent Researcher New York, USA;1. Department of Ophthalmology, Ankara Training and Research Hospital, Altindag, Ankara, Turkey;2. Department of Anesthesiology and Reanimation, Numune Training and Research Hospital, Altindag, Ankara, Turkey;1. Kuopio Research Centre of Geriatric Care, School of Pharmacy, University of Eastern Finland, Finland;2. Research Centre for Comparative Effectiveness and Patient Safety (RECEPS), University of Eastern Finland, Finland
Abstract:ObjectiveMost studies regard orthostatic hypotension (OH) as a causal factor for falls. However, the evidence is lacking for this assumption. We aimed to investigate the relationship between orthostatic hypotension and fall incidents in nursing home residents.MethodsA total of 249 patients was included in a prospective observational cohort study of nursing home residents. Falls were prospectively registered. Cox proportional hazard modelling and the conditional frailty model were used to analyse the relationship between OH and (recurrent) falling.ResultsAmong the 249 patients, 450 falls were recorded during follow-up and OH was present in 93 out of 249 patients. No significant associations were found between OH and the first fall incident (Hazard Ratio (HR) 1.01 (95% Confidence Interval (CI) 0.60–1.69) and recurrent falling (HR 1.21 (95%CI 0.65–2.24)).ConclusionsAlthough falling and OH were both highly prevalent in nursing home residents, no relationship between OH and falling was found.
Keywords:Orthostatic hypotension  Nursing home residents  Fall risk  Recurrent falling
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