A population-level application of a method for estimating the timing of HIV acquisition among migrants to Australia |
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| Authors: | Jonathan M. King Kathy Petoumenos Timothy Dobbins Rebecca J. Guy Richard T. Gray Steven J. Nigro Damin Si Byron Minas Skye McGregor |
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| Affiliation: | 1. The Kirby Institute, UNSW Sydney, Sydney, New South Wales, Australia;2. School of Population Health, UNSW Sydney, Sydney, New South Wales, Australia;3. Communicable Diseases Branch, Health Protection NSW, Sydney, New South Wales, Australia;4. Communicable Diseases Branch, Prevention Division, Queensland Health, Brisbane, Queensland, Australia;5. Communicable Disease Control Directorate, Department of Health WA, Perth, Western Australia, Australia |
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| Abstract: | Introduction Australia has set the goal for the virtual elimination of HIV transmission by the end of 2022, yet accurate information is lacking on the level of HIV transmission occurring among residents. We developed a method for estimating the timing of HIV acquisition among migrants, relative to their arrival in Australia. We then applied this method to surveillance data from the Australian National HIV Registry with the aim of ascertaining the level of HIV transmission among migrants to Australia occurring before and after migration, and to inform appropriate local public health interventions. Methods We developed an algorithm incorporating CD4+ T-cell decline back-projection and enhanced variables (clinical presentation, past HIV testing history and clinician estimate of the place of HIV acquisition) and compared it to a standard algorithm which uses CD4+ T-cell back-projection only. We applied both algorithms to all new HIV diagnoses among migrants to estimate whether HIV infection occurred before or after arrival in Australia. Results Between 1 January 2016 and 31 December 2020, 1909 migrants were newly diagnosed with HIV in Australia, 85% were men, and the median age was 33 years. Using the enhanced algorithm, 932 (49%) were estimated to have acquired HIV after arrival in Australia, 629 (33%) before arrival (from overseas), 250 (13%) close to arrival and 98 (5%) were unable to be classified. Using the standard algorithm, 622 (33%) were estimated to have acquired HIV in Australia, 472 (25%) before arrival, 321 (17%) close to arrival and 494 (26%) were unable to be classified. Conclusions Using our algorithm, close to half of migrants diagnosed with HIV were estimated to have acquired HIV after arrival in Australia, highlighting the need for tailored culturally appropriate testing and prevention programmes to limit HIV transmission and achieve elimination targets. Our method reduced the proportion of HIV cases unable to be classified and can be adopted in other countries with similar HIV surveillance protocols, to inform epidemiology and elimination efforts. |
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| Keywords: | HIV epidemiology public health HIV prevention sexually transmitted infections/diseases men who have sex with men key and vulnerable populations |
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