Editing of the TRIM5 Gene Decreases the Permissiveness of Human T Lymphocytic Cells to HIV-1 |
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Authors: | Kevin Dé saulniers,Levine Ortiz,Caroline Dufour,Alix Claudel,Mé lodie B. Plourde,Natacha Merindol,Lionel Berthoux |
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Affiliation: | Department of Medical Biology, Université du Québec à Trois-Rivières, Trois-Rivières, QC G9A 5H7, Canada; (K.D.); (L.O.); (C.D.); (A.C.); (M.B.P.); (N.M.) |
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Abstract: | |
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Keywords: | HIV-1, TRIM5α , genome editing, CRISPR, restriction factor, interferon |
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