Seroepidemiology ofHelicobacter pylori infection in India |
| |
Authors: | Dr. David Y. Graham Ervin Adam Gurunath T. Reddy Jai Prakash Agarwal Rohit Agarwal Doyle J. Evans Jr. Hoda M. Malaty Dolores G. Evans |
| |
Affiliation: | (1) Department of Medicine and Division of Molecular Virology, Veterans Affairs Medical Center and Baylor College of Medicine, 2002 Holcombe Blvd, 77030 Houston, Texas;(2) Deccan Pathological Institute, Osmania General Hospital, Hyderabad, India;(3) Niloufer Hospital, Hyderabad, India |
| |
Abstract: | Helicobacter pylori (previouslyCampylobacter pylori) is now accepted as the major cause of type B gastritis and thus what is known about the epidemiology of type B gastritis can reasonably be transferred toH. pylori. We used a specific ELISA for anti-H. pylori IgG to study the prevalence ofH. pylori infection in a population of lower socioeconomic class from Hyderabad, India. The results from India were compared to studies from other parts of the world. Two hundred thirty-eight individuals ages 3 to 70 participated. The frequency ofH. pylori infection increased with age (P<0.01) and was >80% by age 20.H. pylori infection was present in 79% of the population studied; there was no gender-related difference in prevalence ofH. pylori infection. IgG antibody against hepatitis A (HAV) was rapidly acquired in Hyderabad; in a subset of 58 children between the ages of 3 and 21 tested, the frequency of anti-HAV was 98.2%. The prevalenc ofH. pylori infection increases with age in both developed and developing countries. The high age-specific prevalence ofH. pylori infection in developing countries is probably a reflection of the lower socioeconomic level of those areas.This work was supported by the research funds from the Department of Veterans Affairs; by grant DK 39919 from the National Institute of Diabetes and Digestive and Kidney Diseases, and by the generous support of Hilda Schwartz. |
| |
Keywords: | Helicobacter pylori seroepidemiology race age-specific socioeconomic group hepatitis A |
本文献已被 SpringerLink 等数据库收录! |
|