经皮冠状动脉介入治疗术后支架内再狭窄的临床研究

目的探讨经皮冠状动脉介入术后支架内再狭窄的影响因素,为预防再狭窄发生提供科学的依据。方法在本院作冠状动脉复查的226例患者的病历资料中随机选取无再狭窄病例45例(无狭窄组),与发生再狭窄的45例患者(再狭窄组)比较术前基本资料(包括性别、年龄、高血压及糖尿病病史、血脂情况、是否吸烟)及冠状动脉造影病变特征(包括病变部位、分型、病变血管支数、病变长度、狭窄程度),分析支架内再狭窄的影响因素。结果男性、吸烟、有高血压及糖尿病病史、病变长度、术前狭窄程度对支架内再狭窄有明显影响,经统计学分析(P<0.05);年龄、血脂水平、病变部位、分型、病变血管支数对支架内再狭窄发生无明显影响(P>0.05)。结论冠状动脉病变长度及狭窄程度对支架内再狭窄有明显影响;男性、吸烟者、有高血压及糖尿病病史的患者易发生支架内再狭窄,应尽早防治。

The Treatment of Postoperative In-stent Restenosis after Percutaneous Coronary Intervention Clinical Research

Objective Explore the influencing factors postoperative in-stent restenosis after percutaneous coronary intervention for the prevention of restenosis to provide a scientific basis.Methods In the hospital for 226 patients with coronary artery reviewed the medical records of randomly selected patients without restenosis in 45(no stenosis),and the occurrence of restenosis in 45 patients(restenosis group) to compare the preoperative basic data(including gender,age,hypertension and diabetes mellitus,hyperlipidemia cases,smoking) and angiographic characteristics of lesions(including lesions,type,lesion count,lesion length,stenosis),analysis of in-stent restenosis factors.Results Male,smoking,hypertension and diabetes mellitus,lesion length,preoperative degree of stenosis of in-stent restenosis significantly affected by statistical analysis(P<0.05);age,lipid levels,lesion location,type,disease blood count of in-stent restenosis had no significant effect(P>0.05).Conclusion Coronary lesion length and degree of stenosis in-stent restenosis had a significant effect;men,smokers,patients with a history of hypertension and diabetes-prone in-stent restenosis,as soon as possible to prevention and treatment.