Chronic recurrent Goodpasture's syndrome |
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Authors: | P S Mehler M W Brunvand M P Hutt R J Anderson |
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Affiliation: | 1. Department of Clinical Laboratory, Jinling Hospital, State Key Laboratory of Analytical Chemistry for Life Science, Advance Research Institute of Life Sciences, Nanjing University, Nanjing 210002, China;2. Department of Pediatric Nephrology, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China;3. College of Life Sciences, Nanjing Normal University, Nanjing 210046, China;4. Department of Science and Technology, Jiangsu Province Hospital of TCM, Nanjing 210029, China;1. Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran;2. School of Advanced Biomedical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran;3. Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran;4. Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran |
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Abstract: | A distinctive case of Goodpasture's syndrome characterized by multiple recurrences occurring over 14 years was observed. Each recurrence followed cessation of prednisone and azathioprine therapy, and reinstitution of this therapy resulted in prompt remission. Initially, both glomerulonephritis and hemoptysis were prominent clinical features. In recent years, hemoptysis has been the predominant clinical problem. This and other cases suggest that Goodpasture's syndrome may comprise a wider disease spectrum than generally appreciated. |
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