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In Vitro Development of Neural Progenitor Cells from Human Embryos
Authors:R A Poltavtseva  A A Rzhaninova  A V Revishchin  M A Aleksandrova  L I Korochkin  V S Repin  G T Sukhikh
Institution:(1) Institute of Biological Medicine, Russia;(2) Institute of Gene Biology, Russia;(3) N. K. Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, Russia;(4) A. N. Severtsov Institute of Ecology and Evolution Problems, Moscow
Abstract:Behavior of stem/progenitor cells from the brain of human embryos during in vitro culturing was studied. Cultured cells from human embryonic brain developed and formed neurospheres heterogeneous by their cell composition. In a serum-containing medium some cells underwent differentiation by the neuronal pathway, while others remained in the stem state.
Keywords:neural stem/progenitor cells in human brain  tissue culture  development  differentiation
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