| 溃疡性结肠炎癌变的回顾性分析 |
| |
| 引用本文： | 龚伟,智发朝,刘思德,陈村龙,潘德寿,白杨,姜泊.溃疡性结肠炎癌变的回顾性分析[J].现代消化及介入诊疗,2010,15(3):128-130. |
| |
| 作者姓名： | 龚伟 智发朝 刘思德 陈村龙 潘德寿 白杨 姜泊 |
| |
| 作者单位： | 南方医科大学南方医院消化内科,510515 |
| |
| 摘 要： | 目的分析558例溃疡性结肠炎(UC)发生结直肠癌的风险以及危险因素,为溃疡性结肠炎相关癌(UC-CRC)的监测、筛查以及预防提供依据。方法 1997年1月至2007年12月南方医院共行结肠镜检查32926例,对其中558例UC患者以及UC-CRC患者的相关临床资料进行回顾性分析。结果在558例UC患者中,发现结直肠癌8例,均为进展期癌,总体风险为1.43%,2组病人在年龄、疾病病程、病变范围、诊断结直肠癌前活检是否有不典型增生、是否使用5-ASA类药物、激素治疗以及是否参加内镜随访等方面有显著性差别。危险因素分析提示,疾病病程、病变范围以及结肠镜检查发现不典型增生为UC-CRC的危险因素;定期内镜随访、5-ASA以及激素治疗可降低UC-RC发病的风险。结论 UC患者有较高癌变的风险,但总体风险较西方国家低;UC病程大于10年、全结肠炎以及活检发现有不典型增生是发生结肠癌的高危因素,定期内镜随访以及5-ASA和激素治疗是UC患者防止发生结直肠癌的保护因素。
|
| 关 键 词： | 溃疡性结肠炎 结直肠癌 |
Ulcerative colitis associated colorectal cancer in ulcerative colitis patients: a retrospective analysis |
| |
| GONG Wei,ZHI Fa-chao,LIU-Side,et al..Ulcerative colitis associated colorectal cancer in ulcerative colitis patients: a retrospective analysis[J].Modern Digestion & Intervention,2010,15(3):128-130. |
| |
| Authors: | GONG Wei ZHI Fa-chao LIU-Side |
| |
| Institution: | GONG Wei,ZHI Fa-chao,LIU-Side,et al. Gastroenterology Department,Nanfang Hospital,Guangzhou,510515,China. |
| |
| Abstract: | Objective To analyze the risk and risk factors of ulcerative colitis(UC) associatedcolorectal cancer (CRC) in 558 UC patients and to provide the evidence for UC associated CRC screening surveillance and prevention. Methods Five hundred and fifty-eight UC patients from the 32,926 patients who received colonoscopy in the endoscopy center of Nanfang Hospital from January 1997 to December 2007 were retro- spectively evaluated. Results CRC was diagnosed in 8 patients in 558 UC patients, and the overall incidence... |
| |
| Keywords: | Ulcerativecolitis Colorectalcancer |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
