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Serum selenium and precursors of cardiovascular risk factors in adolescents
Authors:A Spagnolo  G Morisi  G Marano  G Righetti  A Maietta  A Menotti
Institution:(1) Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanità, V.le Regina Elena, 299, 00161 Rome, Italy;(2) Laboratory of Clinical Biochemistry, Istituto Superiore di Sanità, Rome, Italy;(3) Laboratory of Pharmacology, Istituto Superiore di Sanità, Rome, Italy;(4) Division of Cardiology, S.M. Goretti Hospital, Latina, Italy
Abstract:The aim of this study was to determine, in a population of Italian adolescents, the association of serum selenium levels with precursors of biochemical and anthropometric variables known as being among the major risk factors for cardiovascular diseases in the adult population. The following measurements were taken in a school sample of 627 adolescents (aged 12–13 years): serum selenium, total cholesterol, high density lipoprotein cholesterol, non-HDL cholesterol, height, weight, body mass index, systolic blood pressure and diastolic blood pressure.The serum selenium levels were slightly higher in males (83.1 ± 10.1 mgrg/1) than in females (81.7 ±- 11.0 mgrg/1), but the difference was not statistically significant. Serum selenium was positively correlated with total cholesterol, diastolic blood pressure and HDL cholesterol in both sexes; moreover it was positively correlated with non-HDL cholesterol and negatively correlated with height in males only.Corresponding author.
Keywords:Serum selenium  Precursors of cardiovascular risk factors
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