| 细胞角蛋白19-2G2与肺癌血清学检测其他指标的关系 |
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| 引用本文： | 钱志平,潘美珍. 细胞角蛋白19-2G2与肺癌血清学检测其他指标的关系[J]. 实用医学杂志, 2011, 27(6): 979-981. DOI: 10.3969/j.issn.1006-5725.2011.06.022 |
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| 作者姓名： | 钱志平 潘美珍 |
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| 作者单位： | 1. 江苏省苏州市广济医院,215008
2. 213003江苏省常州市中医院 |
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| 摘 要： | 目的:探讨细胞角蛋白19-2G2(CK19-2G2)与肺癌血清学检测其他指标的关系。方法:用化学发光免疫分析法测定71例肺癌患者血清CK19-2G2的水平,并同步检测临床肿瘤诊断常用的血清学指标CEA、NSE、Cyfra211水平,与52例肺部良性疾病和40例健康体检者进行对照比较。结果:肺癌组血清CK19-2G2水平显著高于肺部良性疾病组和健康对照组(均P<0.01);肺部良性疾病组和健康对照组之间无统计学意义。相关分析显示,肺癌患者血清CK19-2G2水平与CEA、NSE、Cyfra211呈正相关性(r=0.234,P<0.01;r=0.272,P<0.01;r=0.529,P<0.01)。CK192G2针对肺癌的诊断效率为84.05%,高于CEA、NSE和Cyfra211。结论:CK19-2G2与临床常见的肿瘤血清学检测指标CEA、NSE、Cyfra211相关,为一种新的辅助诊断肺癌的血清标记物,其针对肺癌的诊断效率高于CEA、NSE和Cyfra211。
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| 关 键 词： | 肺肿瘤 细胞角蛋白192G2 诊断 |
The relations between CK19-2G2 and the other serologic markers of lung cancer diagnosis |
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| QIAN Zhi-ping,PAN Meizhen. The relations between CK19-2G2 and the other serologic markers of lung cancer diagnosis[J]. The Journal of Practical Medicine, 2011, 27(6): 979-981. DOI: 10.3969/j.issn.1006-5725.2011.06.022 |
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| Authors: | QIAN Zhi-ping PAN Meizhen |
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| Affiliation: | QIAN Zhi-ping*,PAN Meizhen.*Research Laboratory,Guangji Hospital,Suzhou 215008,China |
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| Abstract: | Objective To evaluate the relations between CK19-2G2 and the other serologic markers of lung cancer diagnosis.Methods Chemiluminescence immunoassay was used to detect the level of serum CK19-2G2 in 71 patients with lung cancer,52 patients with benign lung diseases and 40 healthy individuals.The CEA,NSE and Cyfra211 were detected simultaneously.Results The levels of serum CK19-2G2 in patients with lung cancer were significant higher than that in healthy control groups and benign lung diseases groups(all P < ... |
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| Keywords: | Lung neoplasms CK19-2G2 Diagnosis |
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