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| 脑创宁对脑组织含水量和血脑屏障通透性影响 | |
| 引用本文： | 龙子江,王桐生,王祥国,夏坤,王正. 脑创宁对脑组织含水量和血脑屏障通透性影响[J]. 安徽中医学院学报, 2001, 20(2): 41-43 |
| 作者姓名： | 龙子江 王桐生 王祥国 夏坤 王正 |
| 作者单位： | 1. 安徽中医学院中西医结合系 2. 安徽省合肥春生中药研究所 3. 安徽中医学院药学系1997级实习生 |
| 基金项目： | 安徽省合肥市科研项目;［1998］60-10; |
| 摘 要： | 目的：考察脑创宁对闭合性脑外伤小鼠脑水肿、血脑屏障通透性的作用。方法：采用自由落体法复制闭合性脑外伤小鼠模型，测定脑组织含水量和伊思蓝含量。结果：脑创宁可明显减轻模型小鼠脑水肿程度，降低伊思蓝含量，保护血脑屏障。结论：脑创宁对闭合性脑外僵小鼠脑组织有一定的保护作用。 |
| 关 键 词： | 闭合性脑外伤 脑水肿 血脑屏障 脑创宁 中医药疗法 |
| 文章编号： | 1000-2219(2001)02-0041-02 |
| 修稿时间： | 2001-02-20 |
EFFECT OF NAOCHUANGNING ON CEREBRAL EDEMA AND PERMEABILITY OF BLOOD-BRAIN BARRIER |
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| LONG Zi-jiang,WANG Tong-sheng,WANG Xiang-guo,XIA Kun,WANG Zhen. EFFECT OF NAOCHUANGNING ON CEREBRAL EDEMA AND PERMEABILITY OF BLOOD-BRAIN BARRIER[J]. Journal of Anhui Traditional Chinese Medical College, 2001, 20(2): 41-43 | |
| Authors: | LONG Zi-jiang WANG Tong-sheng WANG Xiang-guo XIA Kun WANG Zhen |
| Abstract: | Objective:To research the effect of Naochuangning on cerebral edema and the permeability of blood brain barrier in closed cerebral trauma mice.Method:The freely falling object was used to simulate the animal models of closed cerebral trauma.The content of water and Evans blue of brain tissue were determined.Result:Naochuangning could obviously lessen the level of cerebral edema and cut down the content of Evans blue and protect the blood brain barrier.Conclusion:Naochuangning have protective effects on the brain tissue in closed cerebral trauma mice. |
| Keywords: | Closed cerebral trauma Cerebral edema Blood brain barrier Naochuangning |
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