The effect of atracurium or fazadinium on intra-ocular pressure. A comparative study during induction of general anaesthesia |
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| Authors: | M.P. Tattersall ME BS FFARCS Consultant N. J. Manus MB BS FFARCS Registrar D.M. Jackson FFARCS DObstRCOG Consultant |
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| Affiliation: | Princess Margaret Hospital, Okus Road, Swindon, Wiltshire, SNI 4JU |
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| Abstract: | The effect of atracurium 0.6 mg/kg (group A; n = 11) and fazadinium 1 mg/kg (group F; n = 11) on intraocular pressure (IOP) was investigated in 22 patients during induction of anaesthesia with thiopentone 4 mg/kg and fentanyl 0.015 mg/kg. IOP was significantly reduced (p less than 0.01) in all patients following induction of anaesthesia. Intubation produced a rise in IOP in all patients but this was not statistically significant and remained below pre-induction values. The changes were similar in each group. Both of these neuromuscular blockers appear suitable relaxants to use for intraocular surgery. |
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| Keywords: | Neuromuscular relaxants atracurium, fazadinium Eye intra-ocular pressure |
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