| 茶藤中生物碱成分的研究 |
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| 引用本文： | 王世平,李玲,徐冉,吴君. 茶藤中生物碱成分的研究[J]. 中国药房, 2012, 0(19): 1766-1768 |
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| 作者姓名： | 王世平 李玲 徐冉 吴君 |
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| 作者单位： | 贵阳医学院机能实验室;贵州大学生命科学学院 |
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| 基金项目： | 国家自然科学基金资助项目(30471592) |
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| 摘 要： | 目的:研究茶藤的生物碱类成分。方法:运用多种层析方法对茶藤进行分离与纯化,并根据理化性质和波谱数据对其结构进行鉴定。结果:从茶藤中分离得到4个化合物,分别为斯砍定(Scandine)、柳叶水甘草碱(Tabersonine)、11-羟基柳叶水甘草碱(11-Hydroxytabersonine)、19S-长春里宁(19S-Vindolinine)。4个化合物均为首次从该植物中分离得到。结论:本试验结果可在一定程度上为茶藤的活性研究奠定基础。
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| 关 键 词： | 山橙属 茶藤 生物碱 分离 鉴定 |
Study on the Alkaloids from Melodinus magnificus |
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| WANG Shi-ping,LI Ling,WU Jun. Study on the Alkaloids from Melodinus magnificus[J]. China Pharmacy, 2012, 0(19): 1766-1768 |
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| Authors: | WANG Shi-ping LI Ling WU Jun |
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| Affiliation: | (Functional Laboratory,Guiyang Medical College,Guiyang 550004,China) XU Ran(College of Life Sciences,Guizhou University,Guiyang 550002,China) |
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| Abstract: | OBJECTIVE:To study the alkaloids from Melodinus magnificus.METHODS:Multiply column chromatography techniques were applied for the isolation and purification of M.magnificus.The structures were identified with their physicochemical properties and spectral data.RESULTS:4 compounds were isolated and identified from M.magnificus,such as scandine,tabersonine,11-hydroxytabersonine,19S-vindolinine.All compounds were isolated from the species for the first time.CONCLUSION:The results of trial lay a foundation for the study of the activity of M.magnificus to some extent. |
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| Keywords: | Apocynaceae Melodinus Melodinus magnificus Alkaloids Isolation Identification |
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