| 外源性混合气体对离体豚鼠胃平滑肌收缩功能影响的实验研究 |
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| 引用本文： | 丛华 李涛. 外源性混合气体对离体豚鼠胃平滑肌收缩功能影响的实验研究[J]. 中国医科大学学报, 1990, 19(6): 472-473 |
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| 作者姓名： | 丛华 李涛 |
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| 作者单位： | 中国医科大学基础医学部药理学教研室(丛华，李涛，阮英，郭政东)，中国医科大学基础医学部药理学教研室(李智) |
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| 摘 要： | 用表面灌流法,在有、无外源性混合气体的条件下,比较乙酰胆碱引起的豚鼠胃纵、环肌最大收缩(Cmax)、半数有效量(ED_(50))和营养液pH值的变化。结果:有、无外源性混合气体,对豚鼠胃各部纵、环肌的Cmax、ED_(50)无明显影响;营养液pH值无明显的变化。
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| 关 键 词： | 胃平滑肌 乙酰胆碱 最大收缩 |
EFFECT OF THE EXOGENOUS MIXED GASES ON THE CONTRACTILE FUNCTION OF GASTRIC SMOOTH MUSCLES IN GUINEA PIGS |
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| Chong Hua,et al. EFFECT OF THE EXOGENOUS MIXED GASES ON THE CONTRACTILE FUNCTION OF GASTRIC SMOOTH MUSCLES IN GUINEA PIGS[J]. Journal of China Medical University, 1990, 19(6): 472-473 |
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| Authors: | Chong Hua et al |
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| Affiliation: | Chong Hua,et al Department of Pharmacology |
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| Abstract: | With perfusing on the surface, in functional experiment of isolated gastricsmooth muscles in guinea-pig, we observed Cmax and ED_(50) values for longi-tudinal and circular smooth muscles caused by acetylcholine in different stomachposition, fundus, body and antrum in the presence and absence of exogenousmixed gases. The result indicated that Cmax and ED_(50) values of longitudinaland circular smooth muscles in different stomach position in the presence ofmixed gases were not significantly different from these in absence of it(P>0.05). pH values in physiological nourishing solution did not significantlychanged. |
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| Keywords: | gastric smooth muscles acetylcholine 50% effective dose (ED_(50)) maximum contraction (Cmax) |
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