卵巢癌腹水的研究

目的 对卵巢癌腹水相关因素进行分析，探讨其与临床的关系。方法 收集我院１９９３年１月￣１９９８年１月收治的卵巢癌有腹水患者７２例，回顾性分析卵巢癌腹水的相关因素，并对腹水分别进行细胞学检查找癌细胞，ＣＡ１２３测定和染色体检查。结果 ４０岁以上卵巢癌腹水中癌细胞检出率为７３．５％；腹水发生率为８１．９％；腹水癌细胞阳性Ⅲ期以上者占９１．２％；腹水量〉１０００ｍｌ者腹水中癌细胞阳性率明显增高；卵巢表面

Study on Ascite of Ovarian Cancer

OBJECTIVE: Analysis of correlative factors in ascite of ovarian cancer. METHODS: The clinical data of 72 patients with ovarian cancer admitted to our hospital from 1993 to 1998 were analyzed retrospectively. RESULTS: 73.5% of patients with ovarian cancer had cancer cells in ascite, the incidence of ascite was 81.9%, III and IV stage ovarian cancer with cancer cells in ascite were 91.2%, positive rate of tumor cells obviously increased in cases whose ascite were more than 1,000 ml, in cases with tumor surface infiltration as well as with metastasis to omentum, intestine and diaphragm. CA125 value in ascite without cancer cells was (324.94 +/- 527.64) kU/L, whereas in ascite with cancer cells it was (5,172.64 +/- 1,432.61) kU/L. Whether cancer cells were positive or negative. Chromosomal aneuploidy was detected in two third of the cases. CONCLUSION: Routine examination of cancer cells, chromosome and CA125 in ascite with ovarian cancer may improve the diagnostic accuracy.