LYMPHATIC FUNCTION: THE DISAPPEARANCE RATE OF 131I ALBUMIN FROM THE DERMIS |
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Authors: | JULIA P. ELLIS RONALD MARKS B. JOHN PERRY |
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Affiliation: | Department of Dermatology (Dr Ellis), and Department of Medical Physics and Instrumentation (Dr Perry), St George's Hospital, London, S. W. I. and St John's Hospital for Diseases of the Skin, London (Dr Marks) |
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Abstract: | SUMMARY.— The clearance rate of 131I human serum albumin from the dermis has been measured in 50 patients with normal skin, psoriasis, rosacea and the yellow nail syndrome. In each patient the clearance rate varied with the injection site following a constant pattern such that 131I albumin disappeared most rapidly from the index finger 0·5 cm. from the nail fold, less rapidly from the region 2 cm. from the nail fold, and most slowly from the cheek. The results were reproducible. To what extent these findings reflect true variations in lymphatic function is not yet clear. Preliminary results have shown no significant change in the disappearance rate of 131I human serum albumin in the different diseases studied. |
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