Co-induction of HSP70 and heme oxygenase-1 in macrophages and glia after spinal cord contusion in the rat |
| |
| Authors: | Mautes A E Noble L J |
| |
| Institution: | Neurosurgical Research Laboratory, Saarland University Medical School, Saarland, Germany. |
| |
| Abstract: | HSP70 and heme oxygenase-1 (HO-1) are thought to be markers of cell injury and oxidative stress, respectively. We have immunolocalized these proteins in the spinal cord at 1-14 days after contusion. HSP70 and HO-1 were co-induced in glia and macrophages within the injured segment at all time points. This co-induction may reflect complementary functions that serve to protect these cells as they respond to the postcontusional environment. |
| |
| Keywords: | Heat shock protein Spinal cord contusion Microglia/macrophages Astrocyte |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
