缬沙坦与氨氯地平联合治疗社区老年原发性高血压合并糖尿病患者的临 床效果研究

目的探讨缬沙坦联合氨氯地平治疗社区老年原发性高血压合并糖尿病的效果。方法90例原发性高血压合并糖尿病的老年患者,根据编号顺序分为观察组和对照组,各45例。对照组采取氨氯地平治疗,观察组在对照组基础上使用缬沙坦治疗。对比两组治疗前后血糖、血压、胰岛素水平、不良反应发生情况。结果治疗后,观察组患者空腹血糖、餐后2 h血糖、收缩压、舒张压、胰岛素水平分别为(6.04±0.48)mmol/L、(7.12±0.49)mmol/L、(118.89±3.62)mm Hg(1 mm Hg=0.133 kPa)、(76.68±4.32)mm Hg、(8.87±0.65)mIU/L,均低于对照组的(8.98±0.85)mmol/L、(10.11±0.95)mmol/L、(129.31±4.50)mm Hg、(89.31±3.66)mm Hg、(12.37±0.94)mIU/L,差异有统计学意义(P<0.05)。观察组不良反应发生率为6.67%,低于对照组的17.78%,差异有统计学意义(P<0.05)。结论目前常规治疗老年原发性高血压合并糖尿病的有效方法是缬沙坦联合氨氯地平治疗,可以明显地降血糖及血压,而且不良反应少,更适用于大众群体。社区医疗应加大宣传,遵嘱社区老年人做定期体检,对认知不充分的老年人做好教育宣传工作,为改善老年人的生活质量,提高老年人的健康体魄尽一份力。

Clinical effect of valsartan combined with amlodipine in the treatment of elderly patients with essential hypertension and diabetes mellitus in community

Objective To discuss the effect of valsartan combined with amlodipine in the treatment of elderly patients with essential hypertension and diabetes mellitus in community.Methods A total of 90 elderly patients with essential hypertension and diabetes mellitus were divided into observation group and control group according to the order of admission,with 45 cases in each group.The blood glucose,blood pressure,insulin level and occurrence of adverse reactions before and after treatment were compared between the two groups.Results After treatment,the fasting blood glucose,2 h postprandial blood glucose,systolic blood pressure,diastolic blood pressure,insulin of the observation group were(6.04±0.48)mmol/L,(7.12±0.49)mmol/L,(118.89±3.62)mm Hg(1 mm Hg=0.133 kPa),(76.68±4.32)mm Hg and(8.87±0.65)mIU/L,which were all lower than(8.98±0.85)mmol/L,(10.11±0.95)mmol/L,(129.31±4.50)mm Hg,(89.31±3.66)mm Hg and(12.37±0.94)mIU/L of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions of the observation group was 6.67%,which was lower than 17.78%of the control group,and the difference was statistically significant(P<0.05).Conclusion At present,valsartan combined with amlodipine is an effective method for the treatment of elderly patients with essential hypertension and diabetes mellitus,which can significantly reduce blood glucose and blood pressure with less adverse reactions,and is more suitable for the public.In order to improve the quality of life and the health of the elderly,we should strengthen the publicity of community medical care,ask the elderly to do regular physical examination,and do a good job of education and publicity for the elderly with insufficient cognition.Community medical care should increase publicity,instruct the elderly in the community to take regular physical examinations,and do a good job of education and publicity for the elderly with insufficient cognition,and do their best to improve the quality of life of the elderly and improve their health.