早期妊娠绒毛膜隆起的妊娠结局及临床转归

目的探讨早期妊娠绒毛膜隆起的妊娠结局及临床转归。方法收集2017年1月至2020年3月间在西安市第四医院行阴道超声检查的34537名孕妇的临床资料,其中78名孕妇为早期妊娠伴有绒毛膜隆起,回顾性分析其超声表现及临床预后。结果早期妊娠中绒毛膜隆起检出率占0.23%(78/34537)。在78名早期妊娠伴有绒毛膜隆起的孕妇中,有12名孕妇要求终止妊娠,占15.38%(12/78);其余66名孕妇中,有23名孕妇为早期流产,3名孕妇为中期流产,流产率为39.39%(26/66)。在40名活产孕妇中,绒毛膜隆起平均值为(10.18±5.52)mm,在26名流产孕妇中,绒毛膜隆起平均值为(10.34±5.76)mm,活产孕妇与流产孕妇绒毛膜隆起平均值差异无统计学意义(Z=0.092,P>0.05)。在66名孕妇中,有48名孕妇(72.73%)伴有1个绒毛膜隆起,其中9名孕妇流产(18.75%);有18名孕妇(27.27%)伴有1个以上绒毛膜隆起,其中17名孕妇流产(94.44%);绒毛膜隆起1个与1个以上的孕妇流产率差异有统计学意义(χ^2=31.419,P<0.05)。结论妊娠结局与绒毛膜隆起的大小无关联,与其数量有关。超声诊断早期妊娠伴有绒毛膜隆起有重要的临床意义,应密切随访观察患者,警惕后期发生不良妊娠结局。

Pregnancy outcome and clinical prognosis of pregnant women with chorionic bump in first-trimester of pregnancy

Objective To investigate pregnancy outcomes and clinical prognosis of pregnant women with chorionic bump in first-trimester of pregnancy.Methods The clinical data of 34,537 pregnant women who underwent vaginal ultrasonography in The Fourth Xi’an Municipal Hospital from January 2017 to March 2020 were collected.The ultrasonic fingdings and clinical prognosis of the pregnant women were retrospectively analyzed.Among them,78 pregnant women were found to have chorionic bumps by ultrasonography.Results The incidence of chorionic bump in early pregnancy was 0.22%(78/34537)in this article.Among 78 pregnant women who had chorionic bumps in their early pregnancies,12 pregnant women asked for early termination of their pregnancy.Among the remaining 66 pregnant women,23 pregnant women experienced early abortion and 3 pregnant women experienced midtrimester abortion,and the abortion rate was 39.39%(26/66).The mean chorionic bumps thickness of 40 pregnant women who delivered a live birth was 10.18±5.52 mm,and that of 26 pregnant women who experienced abortion was 10.34±5.76 mm,there was no significant difference in the mean chorionic bumps thickness(Z=0.092,P>0.05).48/66 pregnant women(72.73%)had one chorionic bump(18.75%),of them,9 pregnant women experienced abortion.18/66 pregnant women(27.27%)had more than one chorionic bumps,of them,17 pregnant women experienced abortion(94.44%),there was a significant difference in the abortion rate between these pregnant women with one chorionic bump and those pregnant women with more than one chorionic bumps(χ^2=31.419,P<0.05).Conclusion The pregnancy outcome is not related to the size of chorionic bump but its number.Ultrasound diagnosis of chorionic bumps in the first-trimester of pregnancy is of important clinical significance.Those pregnant women with chorionic bump(s)should be followed-up closely to guard against occurrence of later adverse pregnancy outcomes.