儿童铜绿假单胞菌引起社区获得性尿路感染临床特征及其危险因素分析

目的 分析儿童铜绿假单胞菌引起社区获得性尿路感染的临床特征及其危险因素.方法 选择我院2010年6月～2013年6月住院治疗确诊的112例社区获得性尿路感染患者为研究对象,收集患儿临床资料,采用SPSS19.0软件分析找出铜绿假单胞菌引起社区获得性尿路感染的临床特征及其危险因素,旨在为优化儿童铜绿假单胞菌引起社区获得性尿路感染治疗方案提供参考依据.结果 本研究112例社区获得性尿路感染患者中35例患儿为铜绿假单胞菌致病,占31.25％,3岁以下患儿21例,占60.00％;发病以夏秋季为主20例,占57.14％,且多合并其他基础疾病.多因素Logistic回归分析示基础疾病种类＞3种（β=2.16,OR=8.64）、前1周内有尿路插管史（β=0.81,OR=2.26）和长期使用免疫调节抑制药物史（β=2.30,OR=9.96）是铜绿假单胞菌引起社区获得性尿路感染的危险因素,年龄＞3岁（β=-2.94,OR=0.05）和家属对患儿照顾到位（β=-2.82,OR=0.06）是铜绿假单胞菌引起社区获得性尿路感染的保护因素.结论 铜绿假单胞菌引起社区获得性尿路感染发生率较高,其发生受多种因素的影响,我们应该加强高危患儿的管理,减少铜绿假单胞菌引起社区获得性尿路感染的发生.

Clinical features and risk factors analysis on community acquired urinary tract infection children caused by pseudomonas aeruginosa

Objective To investigate the clinical features and risk factors analysis on community acquired urinary tract infection children caused by pseudomonas aeruginosa. Methods One hundred and twelve community acquired urinary tract infection children who were treated in our hospital from June 2010 to June 2013 were chosen as the research ob- jects.Their clinical data were investigated by self-made questionnaire.And the clinical features and risk factors of com- munity acquired urinary tract infection children were analyzed by single factor analysis and Logistic regression analysis of SPSS19.0 statistical software in order to provide a reference basis on optimizing pseudomonas aeruginosa treatment for community acquired urinary tract infection children. Results Thirty-five community acquired urinary tract infection children infected by pseudomonas aeruginosa.Twenty-one community acquired urinary tract infection children were un- der the age of three years old, accounted for 60.00%; Disease was given priority to with summer fall, accounted for 57.14%（twenty cases）, and they combined the other basic diseases. Multiariable Logistic regression analysis showed that basic diseases〉3 （β=2.16,0R=8.64）, history of urinary tract intubation before one week （β=0.81,0R=2.26） and the history of the long-term use of immunomodulatory drugs （β=2.30,0R=9.96） were risk factors of community ac- quired urinary tract infection children caused by pseudomonas aeruginosa, Age〉 3 years old （β=-2.94,0R=0.05） and taking care of the children in place by their families （β=-2.82, OR=0.06） were protective factors of community acquired urinary tract infection children caused by pseudomonas aeruginos. Conclusion Infection rates of community acquired urinary tract infection children caused by pseudomonas aeruginos were high,it is influenced by many factors, we should strengthen the management of high-risk patients in order to reduce caused by pseudomonas aeruginosa commu- nity acquired urinary tract infection.