舟山地区妊高征孕妇常见血清生化指标调查分析

目的：探讨舟山地区妊高征（pregnancy-induced hypertension，PIH）孕妇的常规血清指标的临床意义。方法选择舟山妇幼保健院2010年1月～2012年12月收治的55例PIH孕妇作为PIH组，随机选取同期的55例正常孕妇作为对照组。采用生化仪测定并比较两组孕妇的血清钙（Ca2＋）、磷（P3＋）、血清总胆固醇（total cesterol，TC）及甘油三酯（triglyceride，TG）的含量。结果两组孕妇在Ca2＋、P3＋、TC上均存在显著差异（P＜0.01或P＜0.05），但TG无显著差异。多因素Logistic回归分析模型表明，P3＋和TC均为PIH的危险因素（P＜0.01或P＜0.05），Ca2＋则为保护因素（P＜0.01）。结论血清Ca2＋、P3＋和TC等常用生化指标可作为海岛地区孕妇PIH的观察指标。

Analysis on serum biochemical indicators in patients with pregnancy-in-duced hypertension in Zhoushan area

Objective To investigate the risk factors of pregnancy-induced hypertension （PIH） in Zhoushan Area. Methods A total of 55 PIH patients who were treated in Zhoushan Women and Children Hospital from January 2010 to December 2012 were enrolled as the PIH group, and another 55 pregnant women without PIH were set as the control group. The serum calcium（Ca2＋）, phosphorus（P3＋）, total cesterol（TC）, and triglyceride（TG） were detected by biochemical analyzer. Univariate and multivariate analyses were performed to reveal the potential correlations between these biochemical indicators and PIH. Results The serum levels of Ca2＋, P3＋, and TC between PIH group and control group were significantly different （P〈0.01 or P〈0.05）, while the TG showed no significant difference between these two groups （P=0.15）. Multivariate Logistic regression analysis showed that serum P3＋and TC were risk factors for PIH （P〈0.01 or P〈0.05） whereas serum Ca2＋was a protective factor （P〈0.01）. Conclusion Serum Ca2＋, P3＋and TC levels can be used for monitoring PIH in the islands.