CRRT联合血液灌流在急性重度有机磷农药中毒中的应用

目的 探讨CRRT联合血液灌流在急性重度有机磷农药中毒中的应用效果.方法 以我院2011年1月～2013年1月间收治的60例急性重度有机磷农药中毒患者为研究对象,随机分为观察组与对照组,所有患者均行基础治疗,观察组患者在此基础上联合应用连续性肾脏替代疗法（CRRT）和血流灌注治疗.比较两组患者临床治疗效果、炎性因子水平及治疗时间之间的差异.结果 观察组患者临床治疗效果优于对照组,炎性反应强度低于对照组,治疗时间少于对照组,其差异有统计学意义（P＜0.05）.结论 CRRT联合血液灌流可以在急性重度有机磷农药中毒中发挥积极作用,其可提高临床治疗效果,有效控制炎症反应,缩短患者临床抢救及治疗时间.

The effect analysis of combined application CRRT and hemoperfusion in the treatment of acute severe organophosphorus pesticide poisoning

Objective To investigate the effect of combined application CRRT and hemoperfusion in the treatment of a- cute severe organophosphorus pesticide poisoning. Methods Sixty patients with acute severe organophosphorus pesticide poisoning were divided into the objective group and control group. The conventional treatment plan was used in the control group and the CRRT and hemoperfusion treatment plan were additional used in the objective group. The clinical effect, inflammatory factor levels and treatment time were compared between the two groups. Results The clinical ef- fect of the objective group was better. The inflammatory factor levels was lower in the objective group. The treatment time in the objective group was less than that in the control group. Conclusion It can get a satisfaction effect to com- bined application CRRT and hemoperfusion in the treatment of acute severe organophosphorus pesticide poisoning, with better clinical effect, lower level of inflammatory factor and less treatment time.