| 食管胃静脉曲张破裂出血患者死亡危险因素分析 |
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| 引用本文： | 蒋晓渠,陈世耀,王慧.食管胃静脉曲张破裂出血患者死亡危险因素分析[J].胃肠病学,2011,16(2):90-93. |
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| 作者姓名： | 蒋晓渠 陈世耀 王慧 |
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| 作者单位： | 1. 上海市第一人民医院分院消化内科,200081
2. 复旦大学附属中山医院消化内科 |
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| 摘 要： | 背景：食管胃静脉曲张破裂出血（EVB）是肝硬化门静脉高压的常见并发症,再出血死亡率高.目的：分析EVB患者入院第1个月内的死亡危险因素.方法：回顾性分析2009年5月～2010年1月101例EVB患者的临床和实验室资料,多因素Logistic回归分析筛选独立死亡危险因素并构建Logistic回归模型,以该模型预测患者的死亡风险并与实际情况行一致性检验.结果：EVB患者入院第1个月内的死亡率为38.6%.存活组和死亡组患者的血红蛋白、白蛋白、血胆固醇、血钠、血氯、血钾、白细胞计数、凝血酶原时间、总胆红素、ALT、血尿素氮、血肌酐、Child-Pugh 评分、出血量、腹水和肝性脑病程度差异均有统计学意义（P＜0.05）.多因素Logistic回归分析示血钠、白细胞计数和Child-Pugh评分是EVB的独立死亡危险因素,以此建立的Logistic回归模型预测死亡的敏感性和特异性分别为69.2%和93.5%,一致性检验κ值为0.653.结论：低钠血症、白细胞计数和Child-Pugh评分是EVB患者入院第1个月内的独立死亡危险因素,以此建立的Logistic回归模型可用于EVB患者死亡风险的预测,且与实际情况的一致性良好.
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| 关 键 词： | 食管和胃静脉曲张 危险因素 回顾性研究 回归分析 |
Analysis of Risk Factors of Death in Patients with Esophagogastric Variceal Bleeding |
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| JIANG Xiaoqu,CHEN Shiyao,WANG Hui.Analysis of Risk Factors of Death in Patients with Esophagogastric Variceal Bleeding[J].Chinese Journal of Gastroenterology,2011,16(2):90-93. |
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| Authors: | JIANG Xiaoqu CHEN Shiyao WANG Hui |
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| Institution: | JIANG Xiaoqu,CHEN Shiyao,WANG Hui.Department of Gastroenterology,Branch of Shanghai First People's Hospital,Shanghai(200081) |
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| Abstract: | Background: Esophagogastric variceal bleeding(EVB) is a common complication of portal hypertension with a high rebleeding mortality.Aims: To define the risk factors of death in EVB patients during the first month of hospitalization.Methods: The clinical and laboratory data of 101 EVB patients from May 2009 to Jan.2010 were analyzed retrospectively.Multivariate Logistic regression analysis was conducted to screen the independent risk factors of death and Logistic regression model was constructed to predict t... |
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| Keywords: | Esophageal and Gastric Varices Risk Factors Retrospective Studies Regression Analysis |
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