肺结核病史者第一秒用力呼气容积的结果分析

目的 通过测定第一秒用力呼气容积（ FEV1 ）,分析肺结核病史者的肺功能特点.方法 对潍坊市部分农村地区40 岁以上的居民进行问卷调查、胸片和肺通气功能检测,取资料完整的1052例进行分析.结果 肺结核病史者的FVC%,FEV1%,FEV1/FVC,吸入支气管舒张剂后FEV1%改善及FEV1/FVC等指标均低于非肺结核病史者,差异均有统计学意义.有慢性气流受限不可逆的肺结核病史者吸入支气管舒张剂后FEV1%改善及FEV1/FVC等指标均显著低于无肺结核病史的COPD者,FEV1/FVC指标无明显差异.有吸烟史肺结核病史者吸入支气管舒张剂后FEV1%改善及FEV1/FVC等指标均低于无吸烟史的肺结核病史者,仅FEV1/FVC差异有统计学意义.结论 肺结核病史者的第一秒呼气容积各项指标均较无肺结核病史者差.与COPD者比较,慢性气流受限不可逆的肺结核病史者的气道阻力及受限程度较高,对支气管舒张剂的反应性较差;吸烟使气流受限不可逆的风险性增高.

Analysis on Forced Expiratory Volume in One Second of Patients with Pulmonary Tuberculosis History

Objective To analyze the lung function characteristics of patients with pulmonary tuberculosis history by measuring forced expiratory volume in one second（ FEV1 ）. Methods A questionnaire survey,chest radiograph,and lung function tests were conducted in some rural residents over the age of 40 in Weifang,and 1052 cases with complete data obtained were analyzed. Results The FVC%, FEV1% ,FEV1/FVC, post-bronchodilator FEV1 % improvement anti FEV1/FVC results of patients with pulmonary tuberculosis history were lower than those without history＇ of puhnonary tuberculosis,and the differences were statistically significant. The FVC%, FEV1%, post-brnn- chodilator FEV1% improvement and FEV1/FVC resuhs of patients with pulmonary tuberculosis history who had irreversible chronic airflow limitation were significantly lower than those without history＂ of pulmnnal7 tuberculosis in patients with COPD,but FEV1/FVC showed no significant differencc. The FVC% , FEV1% , FEV1/FVC, post-hronchodilator FEV1 % improvement and FEV1/FVC results of puhnonary tuberculosis patients with smoke history were lower than those without smoke history, hut statistical signifieance was only fimnd in FEV1/FVC. Conclusion Indicators of expiratory wolume in one second of patients with pulmonary tuberculosis history were worse than those without history of pulmonary tuberculosis. Compared with COPD patients,the degree of airway resistance and limitation were higher in patients with pul- monary tuberculosis history who had irreversible chronic airflow limitation,and the response to bronehodilators was poor. Smoking can increase the risk of irreversible airflow limitation.