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Peptidergic (VIP) nerves in the mammalian choroid plexus |
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| Authors: | Maria Lindvall Jan Alumets Lars Edvinsson Jan Fahrenkrug Rolf Håkanson John Hanko Christer Owman Ove B. Schaffalitzky de Muckadell Frank Sundler |
| Affiliation: | 1. Departments of Histology and Pharmacology, University of Lund, Lund Sweden;2. Department of Clinical Chemistry, Bispebjerg Hospital, Copenhagen Denmark |
| Abstract: | The mammalian choroid plexus was examined by immunohistochemistry and radioimmunoassay for the presence of nerves containing vasoactive intestinal polypeptide (VIP). A moderate number of VIP-immunoreactive nerve fibres were found in choroid plexuses from pig. The corresponding concentration of chemically measured VIP was approx. 10 pmol/g. VIP nerves were few in plexuses from cow, cat and rabbit and rare in plexuses from mouse and rat. Pure porcine VIP produced relaxation of isolated bovine anterior choroidal artery in vitro. |
| Keywords: | Address correspondence to: Dr. Maria Lindvall Department of Histology Biskopsgatan 5 S-223 62 Lund Sweden. |
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