GINA吸入治疗方案与其他疗法治疗儿童哮喘的成本-效果分析

目的研究哮喘治疗的GINA吸入治疗方案与其他疗法的成本-效果分析(CEA)。方法随机病例对照研究,用10 cm线性可视性模拟分数图判定疗效。结果吸入疗法组单次药费(180.6±110.5)元,而其他疗法组为(102.8±53.2)元,吸入疗法组药费显著高于其他疗法组(P<0.01);1 a随访结果表明,吸入疗法组药费(2 608±1 630)元,而其他疗法组需(3 054±2 103)元,显著高于吸入疗法组(P<0.01);吸入疗法组满意分数为(86.8±13.1)%,而其他疗法组仅(53.1±19.7)%(P<0.01),其得到的CEA比分别为30.04和57.51,用吸入治疗后儿童上学缺课情况显著下降(86±15)与(328±94)人天(P均<0.01)。结论吸入治疗较其他抗喘治疗能产生较好的治疗效果,其花费也低于其他疗法组。

Cost-effectiveness analysis in child asthma treated with GINA inhaled therapeutic regimen and other therapy

Objective It is to study the cost-effectiveness analysis(CEA) in asthma treated with GINA inhaled therapeutic regimen and other therapy.Methods Random case-control study was done,and the curative effect was assessed with 10 cm linear visual analogue scale.Results Once cost of inhaled therapy group was(180.6±110.5) Yuan,other therapy group was(102.8±53.2) Yuan.The cost of inhaled therapy group was significant higher than that of other therapy group(P<0.01).After one year,the cost of other therapy group((3?054±2?103) Yuan) was significant higher than that of inhaled therapy group((2?608±1?630) Yuan)(P<0.01).The satisfaction score of inhaled therapy group was(86.8±13.1)% and that of other therapy group was(53.1±19.7)%(P<0.01).The CEA were 30.04 and 57.51 respectively,the loss of schooling was declined significantly((86±15) d and(328±94) d)(P<0.01).Conclusion Inhaled therapy has better effect and low cost than other therapy.