| 散发性颅内破裂动脉瘤的流行病学研究 |
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| 引用本文： | 吴鹏飞,吴安华,王运杰. 散发性颅内破裂动脉瘤的流行病学研究[J]. 中国微侵袭神经外科杂志, 2008, 13(7) |
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| 作者姓名： | 吴鹏飞 吴安华 王运杰 |
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| 作者单位： | [1]中国医科大学附属第一医院神经外科; [2]中国医科大学附属第一医院神经外科,辽宁沈阳110001; [3]辽宁沈阳110001,辽宁沈阳110001; |
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| 摘 要： | 目的探讨散发性颅内破裂动脉瘤的流行病学特点。方法应用病例对照研究,对100例散发性颅内破裂动脉瘤病人及116例非颅内动脉瘤病人进行流行病学调查,采用卡方检验及多元Logistic多因素回归分析对各相关危险因素进行统计学分析。结果单因素分析结果表明:63%的散发性颅内破裂动脉瘤病人在40～59岁之间;颅内动脉瘤组与非颅内动脉瘤组在性别(P=0.036,OR=1.794)、吸烟(P=0.005,OR=2.327)、血压(P=0.005,OR=2.161)和空腹血糖(P<0.001,OR=4.114)等方面的差异具有统计学意义。以年龄、性别、吸烟、饮酒、冠心病史、血压和空腹血糖等因素为自变量,Logistic多因素回归加权分析表明:性别(P<0.001,OR=9.435)、吸烟(P<0.001,OR=0.098)、高血压(P=0.016,OR=2.195)和空腹血糖(P<0.001,OR=4.019)仍与颅内动脉瘤的发生明显相关。结论散发性颅内破裂动脉瘤好发于40～59岁之间;女性、吸烟、高血压及空腹血糖增高是颅内动脉瘤的危险因素。
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| 关 键 词： | 颅内动脉瘤 蛛网膜下腔出血 流行病学 危险因素 |
Epidemiological study of sporadic ruptured intracranial aneurysms |
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| Affiliation: | WU Pengfei; WU Anhua; WANG Yunjie Department of Neurosurgery; First Affiliated Hospital of China Medical University; Shenyang 110001; China; |
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| Abstract: | Objective To investigate the epidemiological feathers of sporadic ruptured intracranial aneurysm (IA). Methods A case-control study including 100 patients with sporadic intracranial ruptured aneurysm and 116 non-intracranial aneurysm controls was performed to analyze the effect of risk factors on the liability of IA. Chi square test and logistic regression model were used for multifactor analysis. Results Univariate analysis showed that 63% of IA patients were at age of 40 to 59 years,and there was statisti... |
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| Keywords: | intracranial aneurysms subarachnoid hemorrhage epidemiology risk factors |
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