难治性分泌性中耳炎致病危险因素分析

目的探讨难治性分泌性中耳炎致病的危险因素及诊治措施。方法回顾性分析我院耳鼻咽喉科2011年1月-2012年12月收治的96例分泌性中耳炎患者的临床资料。探讨性别、年龄、病程、反复上呼吸道感染、咽鼓管功能障碍、慢性鼻窦炎、鼻中隔偏曲、鼻咽癌放疗病史、腺样体肥大、变应性鼻炎、腭裂、乳突气化不良等因素与病情发展为难治性的关系。结果 96例(107耳)分泌性中耳炎患者中,发展为难治性分泌性中耳炎22例(24耳),发生率为22.4%。各项因素中乳突气化不良、变应性鼻炎、鼻咽癌放疗史与难治性分泌性中耳炎的发生具有统计学意义(P<0.01)。结论难治性分泌性中耳炎的发生具有多重性,其中主要危险因素为乳突气化不良、变应性鼻炎、电离辐射损伤。

Analysis of risk factors for refractory secretory otitis media

Objective To analyze the risk factors and therapeutic measures for refractory secretory otitis media. Methods We ret- rospectively analyzed the complete clinical data of 96 patients who had undergone refractory secretory otitis media from January 2011 to December 2012 in order to analyze the relationship between refractoriness and such factors as genders, age, course, repeated in- fection, eustachian tube dysfunction, chronic sinusitis, deflection of nasal septum, nasopharyngeal radiotherapy history, adenoid hypertrophy, allergic rhinitis, cleft palate and mastoid gasification. Results Among the 96 cases （ 107 ears）, 22cases （24 ears） evolved gradually toward refractory secretory otitis media, with an incidence of 22.4%. The predominant influencing factors in the causation of refractoriness were mastoid gasification, allergic rhinitis and nasopharyngeal radiotherapy history, which were statistically correlated with the occurrence of refractory secretory otitis media （P 〈 0.01 ）. Conclusion Refractory secretory otitis media is related to multiple factors mainly including mastoid gasification, allergic rhinitis and nasopharyngeal radiotherapeutic damage.