感音神经性聋成人不同刺激声ASSR反应阈与纯音听阈的相关性分析

目的探讨调制声听性稳态反应(ASSR)、 CE-Chirp ASSR用于评估感音神经性聋成人客观听力的价值。方法对78例(131耳)感音神经性聋成人同时进行纯音听阈和调制声ASSR、 CE-Chirp ASSR测试,比较0.5~4 kHz各频率纯音听阈与调制声ASSR、CE-Chirp ASSR反应阈的相关性及差值。结果 0.5、1、2、4 kHz CE-Chirp ASSR反应阈与纯音听阈的相关系数(分别为0.77、0.73、0.80、0.88)均高于调制声ASSR反应阈与纯音听阈的相关系数(分别为0.64、0.61、0.78、0.84),调制声ASSR、CE-Chirp ASSR反应阈与纯音听阈均具有显著相关性(圴为P<0.01);0.5~4 kHz CE-Chirp ASSR反应阈和纯音听阈的差值(分别为8.09±4.74、10.76±5.86、7.44±7.95、6.11±9.14 dB)均明显小于调制声ASSR反应阈和纯音听阈间的差值(分别为14.31±6.38、13.85±6.25、17.17±6.29、13.58±4.35 dB),差异均有统计学意义(均为P<0.05)。结论 CE-Chirp ASSR快捷可靠,较调制声ASSR能更好地评估感音神经性聋成人的听力。

Correlation of ASSR Evoked and Pure Tone Hearing Thresholds of Different Stimuli in Adults with Sensorineural Hearing Loss

Objective To evaluate the values of different stimuli ASSR in objective hearing threshold assessment in comparison with traditional ASSR and CE-Chirp ASSR evoked and pure tone hearing thresholds.Methods Seventy-eight(131 ears) adults with sensorineural hearing loss were received pure tone threshold tests and traditional ASSR, and CE-Chirp ASSR tests. The pure tone hearing thresholds were compared with the ASSR, CE-Chirp ASSR thresholds for a correlation study.Results The traditional ASSR and CE-Chirp ASSR had significant correlation with the pure tone thresholds. The correlation coefficient between CE-Chirp ASSR and pure tone thresholds was slightly higher than that of traditional ASSR at 500 Hz, 1 000 Hz,2 000 Hz and 4 000 Hz.The mean values of absolute differences between CE-Chirp ASSR-induced and pure-tone hearing thresholds were significantly lower than the traditional ASSR-induced thresholds at 500 Hz,1 000 Hz,2 000 Hz,and 4 000 Hz,and the difference was statistically significant(P<0.05).Conclusion CE-Chirp ASSR is fast, reliable, and better than modulated traditional ASSR in assessing hearing in adults with sensorineural hearing loss.