| 近交培育的豫医无毛小鼠H抗原系统的同源性 |
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| 引用本文： | 康巧珍,金树兴,章金涛,凌雁,王纯耀,祝庆蕃.近交培育的豫医无毛小鼠H抗原系统的同源性[J].郑州大学学报(医学版),1999(4). |
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| 作者姓名： | 康巧珍 金树兴 章金涛 凌雁 王纯耀 祝庆蕃 |
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| 作者单位： | 河南医科大学实验动物中心!郑州450052 |
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| 基金项目： | 河南省科技攻关资助项目 |
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| 摘 要： | 目的：研究豫医无毛小鼠Ｈ 抗原系统的同源性。方法：采用近交培育２０ 代２ 月龄雌性豫医无毛小鼠皮肤异体移植法。结果：经１００ ｄ 观察，受试小鼠无急慢性排斥反应发生，移植皮片全部为永久性接受。结论：豫医无毛小鼠突变种群经２０ 代近交培育，组织相容性抗原一致，基因具有高度同源性
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| 关 键 词： | 皮肤 异体移植 近交 豫医无毛小鼠 H抗原 同源性 |
Study on the homology of H antigens in inbred Yuyi hairless mice |
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| Kang Qiaozhen,Jin Shuxing,Zhang Jintao,Ling Yan,Wang Chunyao,Zhu Qingfan Laboratory Animal Center,Henan Medical University,Zhengzhou?.Study on the homology of H antigens in inbred Yuyi hairless mice[J].Journal of Zhengzhou University: Med Sci,1999(4). |
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| Authors: | Kang Qiaozhen Jin Shuxing Zhang Jintao Ling Yan Wang Chunyao Zhu Qingfan Laboratory Animal Center Henan Medical University Zhengzhou? |
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| Institution: | Kang Qiaozhen,Jin Shuxing,Zhang Jintao,Ling Yan,Wang Chunyao,Zhu Qingfan Laboratory Animal Center,Henan Medical University,Zhengzhou?450052 |
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| Abstract: | Aim:To study the homology of H antigens in Yuyi hairless (YYHL)mice.Methods:Skin isografting was performed on inbred YYHL mice at age of 2 months.Result:There were no acute or chronic exclusions with the tested mice after being observed for 100 days.All the grafts were taken in permanently.Conclusion:The results suggest that the histocompatibility antigens are identical and the genes are provided with highly isogenicity in the mutant strain of YYHL mice after inbeding for 20 generations. |
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| Keywords: | isografting inbred Yuyi Hairless Mice H antigens isogenicity |
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