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三叶人字草止血作用研究
引用本文:周玖瑶,陈蔚文,黄桂英,谭永恒. 三叶人字草止血作用研究[J]. 中国实验方剂学杂志, 2007, 13(3): 65-66
作者姓名:周玖瑶  陈蔚文  黄桂英  谭永恒
作者单位:广州中医药大学药理学教研室,广东广州,510405
基金项目:广州中医药大学邓铁涛研究基金课题(2004009)
摘    要:目的:观察三叶人字草止血作用。方法:用三叶人字草4.0,8.0,16.0g生药,kg给小鼠连续灌胃14d,分别测定小鼠的凝血时间、出血时间及血小板计数。结果:三叶人字草各剂量组和空白对照组比较,凝血时间和出血时间明显缩短(P〈0.05。P〈0.01),血小板计数明显增高(P〈0.05)。结论:三叶人字草具有明显的止血作用和升高血小板作用,升高血小板作用是其止血机理之一。

关 键 词:三叶人字草 止血 出血时间 凝血时间 血小板
文章编号:1005-9903(2007)03-0065-02
收稿时间:2006-07-10
修稿时间:2006-07-10

Experimental Study of Kummerowia Striata(KS) on Stanching Effect
ZHOU Jiu-yao,CHEN Wei-wen,HUANG Gui-ying,TAN Yong-heng. Experimental Study of Kummerowia Striata(KS) on Stanching Effect[J]. China Journal of Experimental Traditional Medical Formulae, 2007, 13(3): 65-66
Authors:ZHOU Jiu-yao  CHEN Wei-wen  HUANG Gui-ying  TAN Yong-heng
Affiliation:Department of Pharmacology, Guangzhou University of TCM, Guangdong Guangzhou 510405, China
Abstract:Objective:To discuss the stanching effect of Kummerowia Striata(KS) on mice.Methods:The mice were given orally with KS 4.0 g/kg(low dose group),8.0 g/kg(moderate dose group) and 16.0 g/kg(high dose group)per day,for 14 days.The coagulation time,the bleeding time were measured and platelets were count in the mice.Results:The coagulation time and bleeding time in the KS three groups were significantly shorter than those in the normal saline group(P<0.05,or P<0.01).KS could significantly increase platelets of mice (P<0.05,or P<0.01).Conclusion:KS had stanching effect and the effect of raising platelets,raising platelets is one of mechanisms of Stanching.
Keywords:Kummerowia Striata  stanching effect   bleeding time   coagulation time   blood platelets
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