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中药穴位敷贴对小鼠实验性病毒性心肌炎的疗效观察
引用本文:李建萍,姚永年,赵英侠,许帼光,王健雄.中药穴位敷贴对小鼠实验性病毒性心肌炎的疗效观察[J].上海中医药杂志,2003,37(1):51-53.
作者姓名:李建萍  姚永年  赵英侠  许帼光  王健雄
作者单位:1. 上海市徐汇区中心医院,上海,200031
2. 上海中医药大学,上海,200032
3. 上海第六人民医院,上海,200233
摘    要:为研究中药穴位敷贴治疗病毒性心肌炎的疗效,将小鼠以CVB3病毒感染制成病毒性心肌炎模型后,随机分为对照组与治疗组。治疗组用中药(黄芪、沙参、党参、丹参、冰片)穴位敷贴,对照组不加以治疗,30d后分别观察小鼠心肌组织病理学改变和超微结构改变并检测血清中CK-MB含量。结果:治疗组小鼠心肌组织病理改变及超微结构改变均较对照组减轻,血清CK-MB含量明显低于对照组(P<0.05)。提示中药穴位敷贴对病毒性心肌炎有一定疗效。

关 键 词:病毒性心肌炎  中药穴位敷贴  心肌组织  病理改变  血清CK-MB  外治法
文章编号:1007-1334(2003)01-0051-03

Study on Herbal Acupoint Application Therapy for Experimental Viral Myocarditis in Mice
Abstract:To explore the clinical efficacy of acupoint application of Chinese medicine in the treatment of viral myocarditis,mice were modeled to contract viral carditis with CVB 3 and then randomized into treatment group and control group.In treatment group,Chinese herbal pills were applied on acupoints;in control group,no treatment was given.After 30 days,the pathological changes and ultrastructure changes of heart tissue were observed;and the content of serum CK MB was lower in treatment group than in control group ( P <0 05).
Keywords:Viral carditis  animal model  acupoint application of Chinese herb  serum CK  MB
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