Disodium cromoglycate inhibits immunoglobulin production in vitro without affecting cell growth in human B cell lines |
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| Authors: | H Kimata A Yoshida C Ishioka H Mikawa |
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| Affiliation: | Department of Pediatrics, Kyoto University Hospital, Japan. |
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| Abstract: | The effect of disodium cromoglycate (DSCG) on human B cell lines (IM-9, GM-1056, and AF-10) was studied. DSCG inhibited immunoglobulin production by these B cell lines without affecting thymidine uptake or cell number. Thus, in addition to its antiallergic function, DSCG may also act as a B cell-modulating reagent in vitro. |
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