Treatment strategy for malignant solid tumors in childhood |
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| Authors: | Ohnuma Naomi Yoshida Hideo Matsunaga Tadashi Kouchi Katsunori Hishiki Tomoro Yamada Shinichi Satoh Yoshiharu Terui Keita |
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| Affiliation: | Pediatric Surgical Department, Chiba University Graduate School of Medicine, Chiba, Japan. |
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| Abstract: | The prognosis for children with malignant solid tumors has improved dramatically in Japan. During the last two decades, various groups have conducted sequential studies of the treatment of children with neuroblastoma, Wilms' tumor, and hepatoblastoma. Most institutes participated in nonrandomized trials designed to evaluate the safety and efficacy of combination chemotherapy, surgery, and radiotherapy in each group study and treated children with these tumors The results are reviewed and areas for future investigation are identified. |
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