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| 比较四联与三联疗法治疗消化性溃疡的疗效 | |
| 引用本文： | 赵刚,钱学兰,林红,钱学梅,贺晓冰. 比较四联与三联疗法治疗消化性溃疡的疗效[J]. 中国临床药理学杂志, 2011, 27(8) |
| 作者姓名： | 赵刚 钱学兰 林红 钱学梅 贺晓冰 |
| 作者单位： | 1. 江汉油田总医院药学部,湖北,潜江,433124 2. 江汉油田总医院内科,湖北,潜江,433124 3. 江汉油田总医院保健科,湖北,潜江,433124 |
| 摘 要： | 目的观察四联与三联疗法对消化性溃疡的治疗作用及根除幽门螺杆菌的效果。方法将胃镜证实为消化性溃疡的患者,随机分为3组,给予不同治疗方案,A,B 2组为四联疗法组,在C组(三联)疗法的基础上,分别加用养胃舒与丽珠得乐。7周后复查胃镜和13C呼气试验。结果 A、B及C 3组的溃疡总愈合率分别为90.9%,100%,86.4%;S2获得率分别为68.2%,73.1%和45.5%;Hp根除率分别为73.3%,76.1%和52.6%;症状缓解率大致相似。3组均无明显药物不良反应发生。结论雷尼替丁三联疗法加用铋剂和养胃舒,均可使S2获得率增加;同时Hp根除率上升,且较安全。 |
| 关 键 词： | 消化性溃疡 幽门螺杆菌 四联疗法 |
Comparison the effects of quadruple and triple chemotherapy for the treatment with peptic ulcer disease |
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| ZHAO Gang,QIAN Xue-lan,LIN Hong,QIAN Xue-mei,HE Xiao-bing. Comparison the effects of quadruple and triple chemotherapy for the treatment with peptic ulcer disease[J]. The Chinese Journal of Clinical Pharmacology, 2011, 27(8) | |
| Authors: | ZHAO Gang QIAN Xue-lan LIN Hong QIAN Xue-mei HE Xiao-bing |
| Affiliation: | ZHAO Gang1a,QIAN Xue-lan1b,LIN Hong1c,QIAN Xue-mei1b,HE Xiao-bing1c(1.a.Department of Pharmacy,b.Intemal Medicine,c.Department of Health,Hubei Jianghan Oilfield General Hospital,Qianjiang 433124,Hubei Province,China) |
| Abstract: | Objective To study the efficacies of quadruple and triple chemotherapy for the treatment with peptic ulcer disease and eradication of helicobacter pylori(HP).Methods HP associated peptic ulcer were randomly divided into three groups(A,B,C groups),give different treatment: C group with triple chemotherapy,while A and B groups with quadruple chemotherap used by Yangweishu capsule and lizon capsule respectively in the basis of triple chemotherapy.Seven weeks after treatment gastroscope or urea breath test(13C-... |
| Keywords: | peptic ulcer helicobacter pylori guadruple chemotherapy |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |