| 复方苯佐卡因凝胶对试验性牙痛模型的影响 |
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| 引用本文： | 韦宝伟,刘布鸣,陈力力,刘元,姚树汉.复方苯佐卡因凝胶对试验性牙痛模型的影响[J].国际口腔医学杂志,2011,38(6):641-642,645. |
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| 作者姓名： | 韦宝伟 刘布鸣 陈力力 刘元 姚树汉 |
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| 作者单位： | 广西中医药研究院 南宁530022 |
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| 摘 要： | 目的 对比仿制药复方苯佐卡因凝胶与其被仿制品Orajel Mouth-Aid (OMA)的镇痛作用.方法 采用电刺激家兔牙髓法和光电刺激大鼠尾巴法.结果 局部给药后,复方苯佐卡因凝胶和OMA均能提高动物痛阈,有良好的镇痛作用且具有剂量依赖性.结论 复方苯佐卡因凝胶和OMA均有镇痛作用且作用强度相当,可用于牙痛的治疗.
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| 关 键 词： | 苯佐卡因 镇痛作用 家兔 大鼠 |
Effects of Benzocaine compound gel on experimental toothache |
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| Wei Baowei,Liu Buming,Chen Lili,Liu Yuan,Yao Shuhan.Effects of Benzocaine compound gel on experimental toothache[J].Journal of International Stomatology,2011,38(6):641-642,645. |
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| Authors: | Wei Baowei Liu Buming Chen Lili Liu Yuan Yao Shuhan |
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| Institution: | Wei Baowei,Liu Buming,Chen Lili,Liu Yuan,Yao Shuhan.(Guangxi Institute of Chinese Medical & Pharmaceutical Science,Nanning 530022,China) |
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| Abstract: | Objective To compare analgesic efficacy of the copied Benzocaine compound gel and its original product Orajel Mouth-Aid,an over the counter drug product made in USA.Methods Pain thresholds in dental pulp of rabbits,and in tail flick of rat model were used.Results By topical application,these two products exhibited dose-dependent analgesic actions in rabbits and rats.Conclusion These two products have analgesic efficacy with similar potency,and they are good for toothache. |
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| Keywords: | Benzocaine analgesic action rabbit rat |
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