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姜黄素衍生物的药理活性及构效关系研究进展
引用本文:葛海霞,周海嫔. 姜黄素衍生物的药理活性及构效关系研究进展[J]. 海峡药学, 2011, 23(10): 12-16
作者姓名:葛海霞  周海嫔
作者单位:浙江湖州师范学院生科院 湖州313000
摘    要:姜黄素具有抗肿瘤、抗炎、抗氧化、抗抑郁和抑制组织因子等多种药理作用.本文综述了近几年姜黄素衍生物药理活性的研究现状,论述了姜黄素及其衍生物的结构与其抗氧化、抗炎和抗肿瘤的药理作用的关系,为姜黄素的开发利用提供基础.

关 键 词:姜黄素衍生物  药理活性  构效关系

Advances in studies on the bioactivity and the structure-activity relationship of curcumin analogues
GE Hai-xia,ZHOU Hai-bin. Advances in studies on the bioactivity and the structure-activity relationship of curcumin analogues[J]. Strait Pharmaceutical Journal, 2011, 23(10): 12-16
Authors:GE Hai-xia  ZHOU Hai-bin
Affiliation:GE Hai-xia,ZHOU Hai-bin(Collage of life Science and technology Huzhou teachers collage,Huzhou 313000)
Abstract:Curcumin has anti-tumor,anti-inflammatory,anti-oxidant,anti-depressant,inhibition of tissue factor and other pharmacological activities.This article reviews the pharmacological activities of curcumin analogues in recent years,the relationship between the structure and the anti-oxidation,anti-inflammatory and anti-cancer pharmacological activities of curcumin analogues were summarized,provide the basis for the development and utilization of curcumin.
Keywords:Curcumin analogues  Pharmacological activities  Structure-activity Relationship  
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