| 氧化应激在糖尿病相关性牙周炎发病中的作用 |
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| 引用本文： | 徐惠霞.氧化应激在糖尿病相关性牙周炎发病中的作用[J].国际口腔医学杂志,2011,0(5):592-595. |
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| 作者姓名： | 徐惠霞 |
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| 作者单位： | 中山大学光华口腔医学院·附属口腔医院牙周科 广州510055 |
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| 基金项目： | 广东省自然科学基金资助项目(8151008901000087) |
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| 摘 要： | 在糖尿病相关性牙周炎发病机制的研究中,糖尿病患者中长期慢性的高糖状态可能通过多个途径诱发氧化应激,局部产生大量的活性氧族(ROS),而ROS可改变信号传导通路引起炎症反应因子的基因和蛋白质表达异常,导致机体炎症应答大大增强,促使牙周炎症发生.本文就高血糖诱发氧化应激的可能途径、氧化应激作用机制、抗氧化物在糖尿病相关性牙...
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| 关 键 词： | 氧化应激 活性氧族 糖尿病 牙周炎 |
Role of oxidative stress in the pathogenesis of diabetes-related periodontitis |
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| Xu Huixia.Role of oxidative stress in the pathogenesis of diabetes-related periodontitis[J].Journal of International Stomatology,2011,0(5):592-595. |
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| Authors: | Xu Huixia |
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| Institution: | Xu Huixia,Fu Yun.(Dept. of Periodontics,Hospital of Stomatology,Guanghua School of Stomatology,Sun Yat-Sen University,Guangzhou 510055,China) |
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| Abstract: | In the research of pathogenesis of diabetes-related periodontitis,oxidative stress could be activated by long-term chronic hyperglycemia of diabetics via multiple processes,which contributes to accumulation of reactive oxygen species(ROS) in periodontal tissues.While ROS alters signal transduction path,leading to abnormality of inflammatory factor's gene and protein expression,which amplify host inflammatory response,ultimately perioodontitis occur.The purpose of this review is to provide an overview of the... |
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| Keywords: | oxidative stress reactive oxygen species diabetes periodontitis |
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