| 哌拉西林/舒巴坦复方制剂的临床应用研究进展 |
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| 引用本文： | 胡华. 哌拉西林/舒巴坦复方制剂的临床应用研究进展[J]. 中国临床药理学杂志, 2011, 27(10) |
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| 作者姓名： | 胡华 |
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| 作者单位： | 山东省胸科医院呼吸科,济南,250013 |
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| 摘 要： | 哌拉西林和舒巴坦联合的复方制剂中的2种组分,在药代动力学上具有很好的同步性,抗菌谱上有协同作用,并且舒巴坦特有的对鲍曼不动杆菌的活性,使哌拉西林/舒巴坦在治疗院内感染方面具有独特的优势。舒巴坦的制备成本低于他唑巴坦,临床应用更经济。
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| 关 键 词： | 哌拉西林/舒巴坦 哌拉西林/他唑巴坦 鲍曼不动杆菌 治疗成本 |
Progress in search for clinical application of piperacillin sodium and sulbactam sodium |
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| HU Hua. Progress in search for clinical application of piperacillin sodium and sulbactam sodium[J]. The Chinese Journal of Clinical Pharmacology, 2011, 27(10) |
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| Authors: | HU Hua |
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| Affiliation: | HU Hua(Respiration Department,Shandong Provincial Chest Hospital,Jinan 250013,China) |
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| Abstract: | The two constituents of piperacillin sulbactam combination praperation have the same pharmacokinetic properties.There was regain the antibiotic activity of pipperacillin and sulbactam.However,the intrinsic activity of sulbactam against Acinetobacter spp.Furthermore,the cost to prepare sulbactam is lower than that of tazobactam.Using piperacillin-sulbactam is more economical than piperacillin-tazobactam in clinical treatment from the point of view of cost saving. |
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| Keywords: | piperacillin-sulbactam piperacillin-tazobactam Acinetobacter baumannii treatment costs |
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