Fournier gangrene associated with Crohn disease |
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Authors: | Jiang T Covington J A Haile C A Murphy J B Rotolo F S Lake A M |
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Institution: | Hospitalist Group, Greater Baltimore Medical Center, Baltimore, MD 21204, USA. |
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Abstract: | A 17-year-old boy presented with Fournier gangrene associated with previously undiagnosed Crohn ileocolitis. Fournier gangrene was managed by débridement, broad-spectrum antibiotics, and hyperbaric oxygen. A diverting ileostomy was performed before skin grafting and scrotal reconstruction. Microscopy of a full-layer surgical sample from the terminal ileum revealed granulomas with multinucleated histiocytes, consistent with Crohn disease. Crohn disease was treated with mesalamine, metronidazole, 6-mercaptopurine, and infliximab. The patient was discharged on hospital day 32. At 6-month follow-up, reconstruction of his scrotum had completely healed. Ostomy output was normal. |
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