妇科恶性肿瘤患者围术期并发深静脉血栓的危险因素分析

[目的]探讨妇科恶性肿瘤患者围术期并发深静脉血栓(D V T)的危险因素.[方法]本研究选取2010年1月至2019年12月发表的妇科恶性肿瘤并发DVT的文献进行Meta分析,探讨妇科肿瘤患者围术期并发DVT的危险因素.[结果]共纳入文献12篇,13项危险因素,包括年龄、体质量指数(BMI)、手术、化疗、肿瘤分期、高血...

Risk Factors of Deep Venous Thrombosis in Patients with Gynecological Malignancies during Perioperative Period

[Objective]To investigate the risk factors of perioperative deep venous thrombosis(DVT)in patients with gynecological malignancies.[Methods]In this study,we selected the literatures of gynecological malignant tumor complicated with DVT published from January 2010 to December 2019 for META-analysis to explore the risk factors of gynecological tumor patients complicated with DVT during perioperative period.[Results]A total of 12 articles were included,with 13 risk factors,including age,body mass index(BMI),opera-tion,chemotherapy,tumor stage,hypertension,history of thrombosis,operation time,blood transfusion,PICC catheterization,hyperlipidemia,diabetes,D-dimer.The statistically significant risk factors were BMI(OR=2.65,95%CI:1.61?4.36,P=0.0001),surgery(OR=2.33,95%CI:1.62?3.36,P<0.0001),chemotherapy(OR=2.08,:1.50?2.90,P<0.0001),tumor stage(OR=2.42,95%CI:1.54?3.8,P<0.0001),hypertension(OR=3.10,95%CI:2.13?4.50,P<0.0001),blood transfusion(OR=7.19,95%CI:2.55?20.30,P=0.0002),PICC catheterization(OR=2.07,95%CI:1.38?3.12,P=0.0005),diabetes(OR=3.66,95%CI:1.78?7.53,P=0.0004),operation time>3 h(OR=1.1,95%CI:1.01?1.20,P=0.03).[Conclusion]BMI,operation,chemotherapy,tumor stage,hypertension,blood transfusion,PICC catheterization,diabetes,operation time hare the risk factors of DVT in the perioperative period of gynecological malignant tumor.It is possible that controlling the above factors can ef-fectively reduce the incidence of DVT.