TCD联合血清D-D检测对急性脑梗死患者颅内动脉狭窄的诊断价值

[目的]探讨经颅多普勒超声(T CD)联合血清D二聚体(D-D)对急性脑梗死颅内动脉狭窄的诊断价值.[方法]选取2018年7月至2020年7月在本院诊治的急性脑梗死患者112例为研究对象.所有患者均接受C T血管造影(CTA)和TCD检查,且均采集静脉血检测其血清D-D水平.比较TCD与CTA检测颅内动脉狭窄的结果,以...

Value of TCD Combined with Serum D-D in Diagnosis of Intracranial Artery Stenosis in Acute Cerebral Infarction

[Objective]To investigate the diagnostie valve of transeranial Doppler sonography(TCD)combined with serum D dimer(D-D)in the diagnosis of intracranial artery stenosis in acute cerebral infarction,[Methods]A total of 112 patients with acute cerebral infarction admitted to our hospital from July 2018 to July 2020 were selected as the research subjects.All patients reeived CT angiography(CTA)and TCD examination,and venous blood was drawn to detect the serum D-D level.The results of TCD and CTA in detecting intraeranial artery stenosis were compared,Using CTA results as the gold standard,the diagnostie value of TCD on intracranial vascular stenosis was analyzed.and receiver operating characteristic curve(ROC)was used to analyze the diagnostic value of serum D-D in the diagnosis of intracranial vascular stenosis,and the area under the curve(AUC)was recorded.The value of TCD combined with serum D-D in the diagno-sis of intracranial vascular stenosis was compared with single detection.[Results]CTA examination results showed that a-mong 112 patients.there were 81 cases of intracranial vascular stenosis and 31 cases of non-stenosis.Overall,202 stenotie vessels were detected by CTA and 191 stenotic vessels were detected by TCD.TCD had a good consistency in the diagno-sis of stenotic vessels,with Kappa value of 0.762.TCD had the highest diagnostic value on MCA vascular stenosis,with sensitivity of 91.76%,positive predietive value of 93.98%and the best consistency of Kappa value=0.852.ROC curve a-nalysis results showed that the AUC value of serum D-D in the diagnosis of intracranial vascular stenosis was 0.714.and the diagnostic value was the highest when the cut off point was>0.85mg/L,and the sensitivity and specificity were 48.15%and 87.10%,respectively.The sensitivity and accuracy of TCD combined with serum DD in the diagnosis of in-tracranial vascular stenosis were 93.83%and 95.54%,respectively,which were significantly higher than those of single detection of serum DD(P<0.05),but there were no signifiant dfferences compared to single dection of TCD(P>0.05).[Conclusion]TCD has a high diagnostice value on intracranial artery stenosis in acute cerebral infarction,espeially for MCA vascular stenosis.TCD combined with serum D-D can improve the diagnostic accuracy.