| 当归醇沉物对体外小鼠脾、胸腺淋巴细胞增殖的影响 |
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| 引用本文： | 夏雪雁,彭仁琇.当归醇沉物对体外小鼠脾、胸腺淋巴细胞增殖的影响[J].中草药,1999,0(2):112-115. |
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| 作者姓名： | 夏雪雁 彭仁琇 |
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| 作者单位： | 湖北医科大学药理教研室,武汉,430071 |
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| 摘 要： | 体外试验中，采用ＭＴＴ比色法测定当归醇沉物对小鼠脾及胸腺淋巴细胞增殖功能的影响，结果显示，０．１６～２．５０ｍｇ／ｍＬ范围内的当归醇沉物能单独或协同ＣｏｎＡ／ＬＰＳ发挥促进小鼠脾脏及胸腺Ｔ，Ｂ淋巴细胞增殖的作用，当归醇沉物尚可对氢化泼尼松（ＨＰ）对ＣｏｎＡ诱导的脾脏及胸腺Ｔ淋巴细胞的增殖反应的抑制作用。
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| 关 键 词： | 当归醇沉物 淋巴细胞增殖 MTT比色法 氢化泼尼松 |
| 收稿时间： | 1998/4/20 0:00:00 |
Effects of Chinese Angelica Tuber (Angelica sinensis) Ethanol Sediments on Mice Spleen and Thymus Lymphocytes Proliferation in vitro |
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| Xia Xueyan and Peng Renxiu.Effects of Chinese Angelica Tuber (Angelica sinensis) Ethanol Sediments on Mice Spleen and Thymus Lymphocytes Proliferation in vitro[J].Chinese Traditional and Herbal Drugs,1999,0(2):112-115. |
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| Authors: | Xia Xueyan and Peng Renxiu |
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| Institution: | Department of Pharmacology, Hubei University of Medical Science,Wuhan 430071;Department of Pharmacology, Hubei University of Medical Science,Wuhan 430071 |
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| Abstract: | Sediment (ESA) obtained from the alcoholic precipitate of extract of tuber of Agelica sinensis (Oliv.)Diels in the preparation of Angelica injection was considered as a waste product. Its effect on lymphocyte proliferation of mice spleen and thymus was tested in vitro by MTT colorimetry. Results showed that at concentrations in the range of 0. 16 ~2. 50 mg/mL. ESA significantly promoted T,B lymphocyte proliferation either alone or with ConA/LPS, and can also antagonize hydroprednisone induced suppression of T lymphocyte proliferation in vitro. |
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| Keywords: | ethanol sediments from tuber of Angelica sinensis (Oliv ) Diels lymphocyte proliferation MTT colorimetry hydroprednisone |
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