| 微小RNA-143-3p靶向调控Kirsten鼠肉瘤病毒癌基因介导丝裂原活化蛋白激酶/细胞外调节蛋白激酶信号通路对胃癌细胞增殖侵袭及上皮间质转化的作用机制 |
| |
| 引用本文： | 魏小果,杨帆,成功,赵鑫. 微小RNA-143-3p靶向调控Kirsten鼠肉瘤病毒癌基因介导丝裂原活化蛋白激酶/细胞外调节蛋白激酶信号通路对胃癌细胞增殖侵袭及上皮间质转化的作用机制[J]. 中华实验外科杂志, 2021, 0(1): 77-80 |
| |
| 作者姓名： | 魏小果 杨帆 成功 赵鑫 |
| |
| 作者单位： | 甘肃省人民医院消化外科;甘肃中医药大学第一临床医学院 |
| |
| 摘 要： | 目的:探讨miR-143-3p靶向调控Kirsten鼠肉瘤病毒癌基因(KRAS)介导丝裂原活化蛋白激酶(MAPK)/细胞外调节蛋白激酶(ERK)信号通路对胃癌细胞增殖和侵袭的作用机制。方法:双荧光素酶报告基因实验验证miR-143-3p与KRAS基因的靶向关系。将购自上海中国科学院的胃癌细胞株转染分组，将筛选人胃癌细胞...
|
| 关 键 词： | 微小RNA 胃癌 增殖 侵袭 |
Effect of microRNA-143-3p regulating V-Ki-ras2 kirsten rat sarcoma viral oncogene homolog on gastric cancer progression through regulating mitogen-activated protein kinase/extracellular regulated protein kinase signaling pathway |
| |
| Wei Xiaoguo,Yang Fan,Cheng Gong,Zhao Xin. Effect of microRNA-143-3p regulating V-Ki-ras2 kirsten rat sarcoma viral oncogene homolog on gastric cancer progression through regulating mitogen-activated protein kinase/extracellular regulated protein kinase signaling pathway[J]. Chinese Journal of Experimental Surgery, 2021, 0(1): 77-80 |
| |
| Authors: | Wei Xiaoguo Yang Fan Cheng Gong Zhao Xin |
| |
| Affiliation: | (Department of Digestive Medicine,People′s Hospital of Gansu Province,Lanzhou 730000,China;First School of Clinical Medicine,Gansu University of Traditional Chinese Medicine,Lanzhou 730099,China) |
| |
| Abstract: | |
| |
| Keywords: | MicroRNA Gastric cancer Proliferation Invasion |
| 本文献已被 维普 等数据库收录！ |
