胎儿宫内生长受限相关临床因素的分析

目的探讨胎儿宫内生长受限(FGR)的相关临床因素。方法对134例胎儿宫内生长受限孕妇的临床资料进行回顾性分析。结果与胎儿宫内生长受限相关的临床因素为重度妊娠高血压综合征、心肺疾病、胎盘及脐带异常、双胎、羊水过少等。其发生率明显高于对照组,差异具有统计学意义(P<0.01)。乡村居民及无产前检查组胎儿宫内生长受限率明显高于对照组,差异有统计学意义(P<0.01)。胎儿宫内生长受限、新生儿窒息、死亡和死胎、死产及新生儿发病率亦明显高于对照组,差异有统计学意义(P<0.01)。结论重度妊娠高血压综合征、心肺疾病、胎盘及脐带异常、双胎、羊水过少等是影响胎儿宫内生长受限的主要临床因素。居住环境及产前监测亦是影响胎儿宫内生长受限发生的重要临床因素。胎儿宫内生长受限是围生期新生儿发病率及死亡的重要原因。

Associated Clinical Factors and Their Impacts on the FGR

Objective To study the associated clinical factors and their impacts on the FGR. Methods Retrospective analyses of clinical data were performed in 134 cases of pregnant woman with FGR. Results The clinical factors of FGR include pregnancy-induced severe hypertension syndrome, heart and lung diseases, serious placenta and cord abnormality, twin pregnancy, oligohydramnios etc. In the FGR group the occurrence of above-mentioned factors are obviously higher than control group(P< 0.01). Rural residents or those without antenatal care are also significantly( P< 0.01) higher than control group. In the FGR group the incidence of following diseases were also obviously higher( P< 0.01): including new born suffocations, still-born baby, still birth and new born disease. Conclusion Pregnancy-induced hypertension syndrome, heart and lung diseases, blood diseases, serious placenta and cord abnormality, twin pregnancy, oligohydramnios are the primary clinical factors leading to FGR. Living environment and prenatal care are also important factors related to FGR. FGR is one of the important reason leading to still-born baby or new born baby disease or death.